WSD0628
Based on 1 Customer Validation
WSD0628 is a brain penetrant and potent ATM inhibitor with profound radiosensitizing effect.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.43%
- CAS. Nr.: 2765448-96-0
- Formel: C23H23F2N5O2
- Molecular Weight:439.46
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Speicherung:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biologische Aktivität
Beschreibung
In Vitro
WSD0628 significantly increased the radiosensitivity of U251 cells in clonogenic survival assays (0 nM vs. 30 nM at 5Gy, p<0.01)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 2765448-96-0
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Appearance Solid
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Molecular Weight 439.46
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Formel C23H23F2N5O2
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Color Off-white to light yellow
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SMILES
CN(C(N1[C@H]2C(F)(F)CN(C)CC2)=O)C3=C1C4=CC(C5=CN=C(OC)C=C5)=CC=C4N=C3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)