B-Raf-IN-20
B-Raf-IN-20 (Compound Z-001) is a B-RAF inhibitor with an IC50 value of 37.80 nM. B-Raf-IN-20 binds to DFG-out/C-helix-in conformation in the B-RAF kinase. B-Raf-IN-20 has anti-cancer activity against non-small cell lung cancer.
For research use only. We do not sell to patients.
- Formula: C34H37F3N4O4
- Molecular Weight:622.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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B-Raf 37.80 nM (IC50) |
Chemical Information
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Molecular Weight 622.68
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Formula C34H37F3N4O4
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SMILES
CC1=CC=C(NC(C2=CC(C(F)(F)F)=NC=C2)=O)C=C1C3=CC(N4CCOCC4)=NC(OC[C@]5(C6)C[C@@H]7C[C@H](C5)C[C@@]6(O)C7)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)