B-Raf-IN-21
B-Raf-IN-21 is a B-Raf kinase inhibitor with a Kd of 4.8 nM and an IC50 of 6 nM. B-Raf-IN-21 can be used for the research of stroke.
For research use only. We do not sell to patients.
- CAS No.: 342434-07-5
- Formula: C18H19ClN4O
- Molecular Weight:342.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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B-Raf 4.8 nM (Kd) |
B-Raf 6 nM (IC50) |
B-Raf-IN-21 (compound 8) potently inhibits B-Raf kinase with an IC50 of 6 nM in a cell-free kinase activity assay[1].
B-Raf-IN-21 binds to B-Raf with a Kd of 4.8 nM in a cell-free fluorescent polarization ligand binding assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 342434-07-5
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Molecular Weight 342.83
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Formula C18H19ClN4O
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SMILES
ClC=1C=CC(=CC1O)C=2NC(=NC2C=3C=CN=CC3)C(C)(C)CN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B-Raf-IN-21 Related Classifications
HY-184875 Related Classifications
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