B-Raf-IN-21
B-Raf-IN-21 is a B-Raf kinase inhibitor with a Kd of 4.8 nM and an IC50 of 6 nM. B-Raf-IN-21 can be used for the research of stroke.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 342434-07-5
- Formule: C18H19ClN4O
- Masse moléculaire:342.83
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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B-Raf 4.8 nM (Kd) |
B-Raf 6 nM (IC50) |
B-Raf-IN-21 (compound 8) potently inhibits B-Raf kinase with an IC50 of 6 nM in a cell-free kinase activity assay[1].
B-Raf-IN-21 binds to B-Raf with a Kd of 4.8 nM in a cell-free fluorescent polarization ligand binding assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 342434-07-5
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Masse moléculaire 342.83
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Formule C18H19ClN4O
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SMILES
ClC=1C=CC(=CC1O)C=2NC(=NC2C=3C=CN=CC3)C(C)(C)CN
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)