2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. BI-167107

BI-167107 

Cat. No.: HY-121251 Purity: 99.98%
COA Handling Instructions

BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM.

For research use only. We do not sell to patients.

BI-167107 Chemical Structure

BI-167107 Chemical Structure

CAS No. : 1202235-68-4

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 385 In-stock
Solution
10 mM * 1 mL in DMSO USD 385 In-stock
Solid
5 mg USD 350 In-stock
10 mg USD 550 In-stock
50 mg USD 1650 In-stock
100 mg USD 2250 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

BI-167107 Related Antibodies

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α adrenergic receptor β adrenergic receptor

  • Biological Activity

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Description

BI-167107 is a high affinity, full agonist that binds to the β2 adrenergic receptor (β2AR) with a dissociation constant Kd of 84 pM[1].

IC50 & Target

Kd: 84 pM (β2AR)[1]
In Vitro

Compared to other βAR ligands, BI-167107 displays nanomolar affinities and slow off-rates[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

BI-167107 Related Antibodies
Molecular Weight

370.44

Appearance

Solid

Formula

C21H26N2O4
CAS No.
SMILES

O=C1NC(C(O)=CC=C2C(O)CNC(C)(CC3=C(C=CC=C3)C)C)=C2OC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 75 mg/mL (202.46 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6995 mL 13.4975 mL 26.9949 mL
5 mM 0.5399 mL 2.6995 mL 5.3990 mL
10 mM 0.2699 mL 1.3497 mL 2.6995 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 3.75 mg/mL (10.12 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 3.75 mg/mL (10.12 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 3.75 mg/mL (10.12 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 99.98%

COA (248 KB) LCMS (261 KB)

Handling Instructions (2659 KB)
References
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BI-167107 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

BI-1671071202235-68-4BI167107BI 167107Adrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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