BMS 186318
BMS 186318 is an HIV protease inhibitor. BMS 186318 exhibits better anti-HIV efficacy when used in combination with reverse transcriptase inhibitors such as Stavudine (HY-B0116) and other protease inhibitors such as Saquinavir (HY-17007). BMS 186318 can be used in antiviral research.
For research use only. We do not sell to patients.
- CAS No.: 161302-40-5
- Formula: C36H54N4O9
- Molecular Weight:686.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CEM-SS | ED50 |
0.1 μM
Compound: 10n
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Inhibitory activity against HIV-1 virus replication as determined by an XTT endpoint by 50%
Inhibitory activity against HIV-1 virus replication as determined by an XTT endpoint by 50%
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[PMID: 8642558] |
| H9 | CC50 |
>100 μM
Compound: 10n
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Inhibitory activity against human T cell lymphoma (H9) growth by 50 %.
Inhibitory activity against human T cell lymphoma (H9) growth by 50 %.
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[PMID: 8642558] |
Chemical Information
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CAS No. 161302-40-5
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Molecular Weight 686.84
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Formula C36H54N4O9
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SMILES
CC(C)(C)OC(N[C@@H](CC1=CC=CC=C1)[C@H](O)CNC[C@@H](O)[C@H](CC2=CC=C(OCC(N3CCOCC3)=O)C=C2)NC(OC(C)(C)C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS 186318 Related Classifications
HY-120616 Related Classifications
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