Bradykinin triacetate
Based on 19 publication(s) in Google Scholar
Bradykinin triacetate is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin triacetate can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain.
For research use only. We do not sell to patients.
- CAS No.: 5979-11-3
- Formula: C56H85N15O17
- Molecular Weight:1240.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) Bradykinin triacetate
More- Autophagy. 2026 Jun 2:1-30.
- Chem Eng J. 2026 Jan 27;530:173437.
- Anal Chem. 2025 Nov 4;97(43):24225-24231. [Abstract]
- Anal Chem. 2024 Aug 17. [Abstract]
- Anal Chem. 2022 Apr 26;94(16):6363-6370. [Abstract]
- Talanta. 2024 Oct 14:282:127045. [Abstract]
- iScience. 2024 May 22;27(6):110075. [Abstract]
- iScience. 2022 Nov 8;25(11):105446. [Abstract]
- ACS Chem Neurosci. 2021 Jul 21;12(14):2619-2628. [Abstract]
- J Am Soc Mass Spectrom. 2020 Jul 5. [Abstract]
- SLAS Discov. 2019 Feb;24(2):158-168. [Abstract]
- World J Surg Oncol. 2019 Feb 27;17(1):44. [Abstract]
- Biochem Biophys Res Commun. 2024 Dec 31:746:151265. [Abstract]
- Rapid Commun Mass Spectrom. 2023 Feb 15;37(3):e9429. [Abstract]
- Int J Mass Spectrom. 14 October 2021, 116727.
- Int Heart J. 2025 May 31;66(3):485-496. [Abstract]
- bioRxiv. 2026 Mar 30.
- bioRxiv. 2025 Sep 28.
- bioRxiv. 2023 Sep 1.
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WB
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Flow Cytometry
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Cell Imaging/Staining
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Cell Imaging/Staining
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Histological Imaging/Staining
All Endogenous Metabolite Isoforms
MoreAll Bradykinin Receptor Isoforms
More
Biological Activity
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Human Endogenous Metabolite |
Chemical Information
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CAS No. 5979-11-3
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Molecular Weight 1240.36
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Formula C56H85N15O17
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Sequence
Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
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Sequence Shortening
RPPGFSPFR
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (19)
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Journal Impact Factor
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Most Recent
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Anal Chem
Two-Dimensional FAIMS-TIMS Separation for Probing Structural Diversity of Peptides with Resolution Exceeding 6500. [Abstract]2025 Nov 4;97(43):24225-24231. PMID: 41116333 -
Anal Chem
Racetrack FAIMS for High-Resolution and High-Sensitivity Characterization of Peptide Conformers. [Abstract]2024 Aug 17. PMID: 39153009 -
Anal Chem
Two-Dimensional FAIMS-IMS Characterization of Peptide Conformers with Resolution Exceeding 1000. [Abstract]2022 Apr 26;94(16):6363-6370. PMID: 35412805 -
Talanta
A robust polymetallic-coated sheathless interface with high acid and alkali resistance for coupling capillary electrophoresis with mass spectrometry. [Abstract]2024 Oct 14:282:127045. PMID: 39418980 -
iScience
Bradykinin induces acute kidney injury after hypothermic circulatory arrest through the repression of the Nrf2-xCT pathway. [Abstract]2024 May 22;27(6):110075. PMID: 38868208
Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2024 May 22;27(6):110075. [Abstract]
Representative Western blot images of Nrf2, xCT and GPX4 expression in HK-2 cells treated with 100 μM H2O2 and different concentrations of Bradykinin (0, 10, 50, 100, 500, 1000 nM) for 24 h.
Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2024 May 22;27(6):110075. [Abstract]
Flow cytometry of reactive oxygen species (ROS) in HK-2 cells treated with 100 μM H2O2 alone or 100 μM H2O2 plus 100 nM Bradykinin.
Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2024 May 22;27(6):110075. [Abstract]
Representative microscopy images of H2DCFDA-stained HK-2 cells treated with 100 μM H2O2 alone or 100 μM H2O2 plus 100 nM Bradykinin to detect ROS.
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iScience
2022 Nov 8;25(11):105446. PMID: 36388955
Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2022 Nov 8;25(11):105446. [Abstract]
Fluo-4 direct staining shows the Bradykinin (100 nM)-induced global Ca2+ transients in the KO myoblast versus CTR.
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ACS Chem Neurosci
2021 Jul 21;12(14):2619-2628. PMID: 34184863 -
J Am Soc Mass Spectrom
Wire Desorption Combined with Electrospray Ionization Mass Spectrometry: Direct Analysis of Small Organic and Large Biological Compounds. [Abstract]2020 Jul 5. PMID: 32559077 -
SLAS Discov
A New Model of Sensorial Neuron-Like Cells for HTS of Novel Analgesics for Neuropathic Pain. [Abstract]2019 Feb;24(2):158-168. PMID: 30383474 -
World J Surg Oncol
2019 Feb 27;17(1):44. PMID: 30813916
Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: World J Surg Oncol. 2019 Feb 27;17(1):44. [Abstract]
H&E staining showed the flaps from rats treated with Bradykinin (150 μg/kg, i.p.) showed more neovascularization and less necrosis than those from the control group.
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Biochem Biophys Res Commun
Bradykinin attenuates NiSO4-induced autophagy in MIN6 cells and protects islet function in mice by regulating the PI3K/AKT/mTOR signaling pathway. [Abstract]2024 Dec 31:746:151265. PMID: 39756208 -
Rapid Commun Mass Spectrom
Two-step particle swarm optimization algorithm for effective deconvolution and resolution enhancement of various overlapping peaks. [Abstract]2023 Feb 15;37(3):e9429. PMID: 36346291 -
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Int Heart J
Decrease in Caveolae-Gαq Interaction Mediates Pressure Overload-Induced Cardiac Remodeling in Rats. [Abstract]2025 May 31;66(3):485-496. PMID: 40368774 -
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Purity & Documentation
References
[1]. Hornig B, et al. Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors inhumans. Circulation. 1997 Mar 4;95(5):1115-8. [Content Brief]
[2]. Wang G, et al. Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells. Oncol Rep. 2014 Oct;32(4):1709-14. [Content Brief]
[3]. Dong R, et al. Exogenous Bradykinin Inhibits Tissue Factor Induction and Deep Vein Thrombosis via Activating the eNOS/Phosphoinositide 3-Kinase/Akt Signaling Pathway. Cell Physiol Biochem. 2015;37(4):1592-606. [Content Brief]
[4]. Uchida S, et al. Afferent fibers involved in the bradykinin-induced cardiovascular reflexes from the ovary in rats. Auton Neurosci. 2015 Dec;193:57-62. [Content Brief]
[5]. Liu LT, et al. Effect of vascular bradykinin on pancreatic microcirculation and hemorheology in rats with severe acute pancreatitis. Eur Rev Med Pharmacol Sci. 2015;19(14):2646-50. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)