1. Metabolic Enzyme/Protease GPCR/G Protein
  2. Endogenous Metabolite Bradykinin Receptor Ser/Thr Protease
  3. Bradykinin triacetate

Bradykinin triacetate is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin triacetate can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain.

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CAS No. : 5979-11-3

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Top Publications Citing Use of Products

    Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2024 May 22;27(6):110075.

    Representative Western blot images of Nrf2, xCT and GPX4 expression in HK-2 cells treated with 100 μM H2O2 and different concentrations of Bradykinin (0, 10, 50, 100, 500, 1000 nM) for 24 h.

    Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2024 May 22;27(6):110075.

    Flow cytometry of reactive oxygen species (ROS) in HK-2 cells treated with 100 μM H2O2 alone or 100 μM H2O2 plus 100 nM Bradykinin.

    Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2024 May 22;27(6):110075.

    Representative microscopy images of H2DCFDA-stained HK-2 cells treated with 100 μM H2O2 alone or 100 μM H2O2 plus 100 nM Bradykinin to detect ROS.

    Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: iScience. 2022 Nov 8;25(11):105446.

    Fluo-4 direct staining shows the Bradykinin (100 nM)-induced global Ca2+ transients in the KO myoblast versus CTR.

    Bradykinin triacetate purchased from MedChemExpress. Usage Cited in: World J Surg Oncol. 2019 Feb 27;17(1):44.  [Abstract]

    H&E staining showed the flaps from rats treated with Bradykinin (150 μg/kg, i.p.) showed more neovascularization and less necrosis than those from the control group.

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    Description

    Bradykinin triacetate is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin triacetate can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain[1][2][3][4][5].

    IC50 & Target

    Human Endogenous Metabolite

     

    Molecular Weight

    1240.36

    Formula

    C56H85N15O17

    CAS No.
    Sequence

    Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg

    Sequence Shortening

    RPPGFSPFR

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
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    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Product Name:
    Bradykinin triacetate
    Cat. No.:
    HY-P0206B
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