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Cat. No.: HY-169267

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BRD-K44839765

BRD-K44839765 is selective against Bcl-2 with an IC₅₀ value of 5.6 μM in IMR-90 cell. BRD-K44839765 has oral activity.

For research use only. We do not sell to patients.

CAS No.: 303066-86-6
Formula: C₂₃H₁₉N₃O₂S₂
Molecular Weight:433.55

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

BRD-K44839765 Chemical Structure

CAS No.: 303066-86-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BRD-K44839765 is selective against Bcl-2 with an IC₅₀ value of 5.6 μM in IMR-90 cell. BRD-K44839765 has oral activity^[1].

All Bcl-2 Family Isoforms :

Chemical Information

CAS No. 303066-86-6
Molecular Weight 433.55
Formula C₂₃H₁₉N₃O₂S₂
SMILES

CC1=CC=CC=C1C(NC2=CC3=C(N=C(S3)SCC(NC4=CC=CC=C4)=O)C=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Felix Wong, et al. Discovering small-molecule senolytics with deep neural networks. Nat Aging. 2023 Jun;3(6):734-750. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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BRD-K44839765

All Bcl-2 Family Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BRD-K44839765 Related Classifications

HY-169267 Related Classifications