2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. BZAD-01

BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation.

For research use only. We do not sell to patients.

BZAD-01 Chemical Structure

BZAD-01 Chemical Structure

CAS No. : 305339-41-7

Size Price Stock Quantity
1 mg USD 142 In-stock
5 mg USD 300 In-stock
10 mg USD 450 In-stock
25 mg USD 950 In-stock
50 mg USD 1500 In-stock
100 mg USD 2400 In-stock
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Based on 1 publication(s) in Google Scholar

BZAD-01 Related Antibodies

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Description

BZAD-01 is a potent, selective and orally active inhibitor of NMDA NR2B subunit, with a Ki of 72 nM. BZAD-01 can improve postural asymmetry as well as Apomorphine-induced rotation[1].

Molecular Weight

362.27

Formula

C16H12F6N2O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N=C(NCC1=C(C(F)(F)F)C=CC=C1)C2=CC=C(C=C2)OC(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

Methanol : 250 mg/mL (690.09 mM; Need ultrasonic)

DMSO : 100 mg/mL (276.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7604 mL 13.8019 mL 27.6037 mL
5 mM 0.5521 mL 2.7604 mL 5.5207 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / Methanol 1 mM 2.7604 mL 13.8019 mL 27.6037 mL 69.0093 mL
5 mM 0.5521 mL 2.7604 mL 5.5207 mL 13.8019 mL
10 mM 0.2760 mL 1.3802 mL 2.7604 mL 6.9009 mL
15 mM 0.1840 mL 0.9201 mL 1.8402 mL 4.6006 mL
20 mM 0.1380 mL 0.6901 mL 1.3802 mL 3.4505 mL
25 mM 0.1104 mL 0.5521 mL 1.1041 mL 2.7604 mL
30 mM 0.0920 mL 0.4601 mL 0.9201 mL 2.3003 mL
40 mM 0.0690 mL 0.3450 mL 0.6901 mL 1.7252 mL
50 mM 0.0552 mL 0.2760 mL 0.5521 mL 1.3802 mL
60 mM 0.0460 mL 0.2300 mL 0.4601 mL 1.1502 mL
80 mM 0.0345 mL 0.1725 mL 0.3450 mL 0.8626 mL
100 mM 0.0276 mL 0.1380 mL 0.2760 mL 0.6901 mL
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BZAD-01 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BZAD-01305339-41-7BZAD01BZAD 01iGluRIonotropic glutamate receptorsNMDANR2BInhibitorinhibitorinhibit

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