c-Met-IN-24
c-Met-IN-24 (compound 3g) is a dual-target inhibitor of STAT-3 (=4.7 μM) and c-MET (=12.67 μM) with anticancer activity. c-Met-IN-24 arrests the G2/M cell cycle and induces apoptosis in SNB-75 cells. c-Met-IN-24 can be used in the study of central nervous system cancers.
For research use only. We do not sell to patients.
- Formula: C20H15ClN4O4S
- Molecular Weight:442.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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STAT3 4.7 μM (IC50) |
c-Met 12.67 μM (IC50) |
Chemical Information
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Molecular Weight 442.88
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Formula C20H15ClN4O4S
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SMILES
COC1=CC=CC2=C1OC(C(C3=CSC(NNC(NC4=CC=C(Cl)C=C4)=O)=N3)=C2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)