C3N-Dbn-Trp2
C3N-Dbn-Trp2 is an inhibitor for ATP-binding cassette transporter ABCB1. C3N-Dbn-Trp2 inhibits the ABCB1-mediated Rhodamine 123 (HY-D0816) efflux in cells HEK293T and HCT-15 with IC50 of 5.9 µM and 2.2 µM. C3N-Dbn-Trp2 inhibits the Doxorubicin (HY-15142A) efflux, enhances the cytotoxicity of Doxorubicin in ABCB1-expressing cells.
For research use only. We do not sell to patients.
- CAS No.: 2631659-57-7
- Formula: C36H32N4O2
- Molecular Weight:552.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2631659-57-7
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Molecular Weight 552.66
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Formula C36H32N4O2
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SMILES
[H][C@@]12N(CC3=CC=CC=C3)C4=CC=CC=C4[C@]1(CC5=CC=CC=C5)C[C@]6([H])N2C([C@@](CC7=CNC8=C7C=CC=C8)([H])NC6=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
C3N-Dbn-Trp2 Related Classifications
HY-162714 Related Classifications
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