2,4-D-d5
2,4-D-d5 (2,4-Dichlorophenoxyacetic acid-d5) is the deuterium labeled 2,4-D (HY-18572). 2,4-D (2,4-Dichlorophenoxyacetic acid) is a selective systemic herbicide for the control of broad-leaved weeds. 2,4-D acts as a plant hormone, causing uncontrolled growth in the meristematic tissues. 2,4-D inhibits DNA and protein synthesis and thereby prevents normal plant growth and development.
For research use only. We do not sell to patients.
- Purity: 99.39%
- CAS No.: 352438-69-8
- Formula: C8HD5Cl2O3
- Molecular Weight:226.07
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Storage:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 352438-69-8
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Unlabeled Cas 94-75-7
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Appearance Solid
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Molecular Weight 226.07
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Formula C8HD5Cl2O3
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Color White to light yellow
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SMILES
OC(C([2H])([2H])OC1=C(C([2H])=C(C([2H])=C1[2H])Cl)Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
DMSO : 100 mg/mL (442.34 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57(2):302-10. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4234 mL | 22.1170 mL | 44.2341 mL | 110.5852 mL |
| 5 mM | 0.8847 mL | 4.4234 mL | 8.8468 mL | 22.1170 mL | |
| 10 mM | 0.4423 mL | 2.2117 mL | 4.4234 mL | 11.0585 mL | |
| 15 mM | 0.2949 mL | 1.4745 mL | 2.9489 mL | 7.3723 mL | |
| 20 mM | 0.2212 mL | 1.1059 mL | 2.2117 mL | 5.5293 mL | |
| 25 mM | 0.1769 mL | 0.8847 mL | 1.7694 mL | 4.4234 mL | |
| 30 mM | 0.1474 mL | 0.7372 mL | 1.4745 mL | 3.6862 mL | |
| 40 mM | 0.1106 mL | 0.5529 mL | 1.1059 mL | 2.7646 mL | |
| 50 mM | 0.0885 mL | 0.4423 mL | 0.8847 mL | 2.2117 mL | |
| 60 mM | 0.0737 mL | 0.3686 mL | 0.7372 mL | 1.8431 mL | |
| 80 mM | 0.0553 mL | 0.2765 mL | 0.5529 mL | 1.3823 mL | |
| 100 mM | 0.0442 mL | 0.2212 mL | 0.4423 mL | 1.1059 mL |
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