3,5-Dinitrocatechol (Standard)
3,5-Dinitrocatechol (Standard) (OR-486 (Standard); 3,5-Dinitropyrocatechol (Standard)) is the analytical standard of 3,5-Dinitrocatechol (HY-100959). This product is intended for research and analytical applications. 3,5-Dinitrocatechol (OR-486) is an orally active, blood-brain barrier-permeable selective catechol-O-methyltransferase (COMT) inhibitor. 3,5-Dinitrocatechol can be used in research related to Parkinson's disease, pheochromocytoma and adult cataract.
For research use only. We do not sell to patients.
- CAS No.: 7659-29-2
- Formula: C6H4N2O6
- Molecular Weight:200.11
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 7659-29-2
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Molecular Weight 200.11
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Formula C6H4N2O6
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SMILES
OC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O
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Synonyms
OR-486 (Standard); 3,5-Dinitropyrocatechol (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Nissinen E, et al. Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat. European journal of pharmacology. 1988 Aug 24;153(2-3):263-9. [Content Brief]
[2]. Yamaki F, et al. Effects of Catecholamine Metabolites on Beta-Adrenoceptor-Mediated Relaxation of Smooth Muscle: Evaluation in Mouse and Guinea-Pig Trachea and Rat Aorta. Biological & pharmaceutical bulletin. 2020;43(3):493-502. [Content Brief]
[5]. Vieira-Coelho MA, et al. Effects of tolcapone upon soluble and membrane-bound brain and liver catechol-O-methyltransferase. Brain research. 1999 Mar 06;821(1):69-78. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)