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Cat. No.: HY-113683

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AZ 12488024

(Synonyms: AZD7268)

AZ 12488024 (AZD7268) is a SNC80 (HY-101202) derivative and a δ-opioid receptor agonist. AZ 12488024 is available for research into major depressive disorder.

For research use only. We do not sell to patients.

CAS No.: 1018988-00-5
Formula: C₂₉H₃₀N₄O₂S
Molecular Weight:498.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

AZ 12488024 Chemical Structure

CAS No.: 1018988-00-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

AZ 12488024 (AZD7268) is a SNC80 (HY-101202) derivative and a δ-opioid receptor agonist. AZ 12488024 is available for research into major depressive disorder^[1].

All Opioid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	0.28 nM Compound: 20	Displacement of radiolabeled iodinated deltorphin 2 from delta opioid receptor expressed in HEK293 cell membranes Displacement of radiolabeled iodinated deltorphin 2 from delta opioid receptor expressed in HEK293 cell membranes	[PMID: 22197137]
HEK293	IC₅₀	460 nM Compound: 20	Displacement of radiolabeled FK33-824 from mu opioid receptor expressed in HEK293 cell membranes Displacement of radiolabeled FK33-824 from mu opioid receptor expressed in HEK293 cell membranes	[PMID: 22197137]

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1018988-00-5
Molecular Weight 498.64
Formula C₂₉H₃₀N₄O₂S
SMILES

O=C(C1=CC=C(C=C1)/C(C2=C3N=CC=CC3=CC=C2)=C4CCN(CC\4)CC5=CSC=N5)N(C)CCO
Synonyms

AZD7268
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Fujii H, et al. Non-peptidic δ opioid receptor agonists and antagonists (2000–2012)[J]. Expert Opinion on Therapeutic Patents, 2013, 23(9): 1181-1208. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References

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AZ 12488024

All Opioid Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

AZ 12488024 Related Classifications

HY-113683 Related Classifications