8-Bromoadenine
Based on 1 Customer Validation
8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium.
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- Pureté : 98.92%
- CAS No.: 6974-78-3
- Formule: C5H4BrN5
- Masse moléculaire:214.02
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
In Vitro
8-Bromoadenine (0.1 mM; 30-90 min) inhibits DNA single-strand break repair in HeLa-M cell monolayer cultures. And after γ irradiation, the quality of DNA synthesized by cells is lower than that of DNA synthesized by cells without purine addition[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 6974-78-3
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Appearance Solid
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Masse moléculaire 214.02
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Formule C5H4BrN5
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Color Off-white to yellow
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SMILES
BrC1=NC2=C(N1)C(N)=NC=N2
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Synonyms
8-Bromo-9H-purin-6-amine
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
In Vitro:
0.1 M NaOH : 0.2 mg/mL (0.93 mM; ultrasonic and warming and heat to 60°C)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
8-Bromoadenine Related Classifications
HY-W076740 Related Classifications
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