Alizapride
Based on 1 publication(s) in Google Scholar
Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride also used in human digestive disorders.
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- CAS No.: 59338-93-1
- Formule: C16H21N5O2
- Masse moléculaire:315.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Alizapride
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Activité biologique
Dopamine 2 receptor
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Duncan–Hartley guinea pigs[2]
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Dosage:2.5, 5, 10, 25 μg/kg
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Administration:Alizapride (2.5, 5, 10, 25 μg/kg; SC; 7 consecutive days)
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Result:Reduced the clearance of IgG-sensitized RBCs.
Chemical Information
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CAS No. 59338-93-1
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Masse moléculaire 315.37
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Formule C16H21N5O2
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SMILES
O=C(C1=C(OC)C=C(NN=N2)C2=C1)NCC3N(CC=C)CCC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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bioRxiv
A drug repurposing screen reveals dopamine signaling as a candidate therapeutic pathway for PIGA-CDG. [Abstract]2026 Apr 18:2026.04.17.719256. PMID: 42039650
Pureté et documentation
Références
[1]. P L Warzee, et al. Manometric study of the activity of alizapride on the motor function of the human sphincter of Oddi. J Clin Pharm Ther. 1988 Aug;13(4):281-4. [Content Brief]
[2]. Gomez, et al. Macrophage Fcgamma receptors expression is altered by treatment with dopaminergic drugs. Clinical immunology (Orlando, Fla.) vol. 90,3 (1999): 375-87. [Content Brief]
[3]. Seng, et al. Anti-emetic effect of high-dose metoclopramide vs alizapride--a randomised crossover study. British journal of clinical pharmacology vol. 38,3 (1994): 282-4. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Alizapride Related Classifications
HY-A0125 Related Classifications
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