Angiotensin I (human, mouse, rat)
Based on 3 publication(s) in Google Scholar
Angiotensin I is a decapeptide hormone. Angiotensin I is the precursor of Angiotensin II (HY-13948). Angiotensin I can be used in the study of cardiovascular diseases such as hypertension and vasospasm.
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- Pureté: 99.70%
- CAS No.: 484-42-4
- Formule: C62H89N17O14
- Masse moléculaire:1296.48
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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HY-13948
Angiotensin II human -
HY-P1540
Angiotensin III, human, mouse -
HY-12403
Talfirastide -
HY-B0368
Captopril -
HY-P0206
Bradykinin -
HY-P0059
Teriparatide -
HY-13948A
Angiotensin II human acetate -
HY-P1515A
Angiotensin II (3-8), human TFA -
HY-P1839
Angiotensin I/II (1-5) -
HY-P1829
Angiotensin I/II (1-6) -
HY-P1050
COG 133 -
HY-17512
Losartan
Publications Citing Use of MedChemExpress (MCE) Angiotensin I (human, mouse, rat)
MoreVoir tous les produits spécifiques à Isoform Endogenous Metabolite
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Activité biologique
Description
IC50 & Target
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Human Endogenous Metabolite |
In Vitro
Angiotensin I (10 nM-1 μM) causes dose-dependent contraction in helical strips of canine cerebral artery with intact endothelium[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 484-42-4
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Appearance Solid
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Masse moléculaire 1296.48
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Formule C62H89N17O14
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Color White to off-white
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Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu
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Sequence Shortening
DRVYIHPFHL
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (3)
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Journal Impact Factor
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Most Recent
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Phytomedicine
Bioactive equivalent combinatorial components of Xiao-Xu-Ming decoction inhibit the calmodulin-mediated MLCK/MLC axis to attenuate coronary artery spasm. [Abstract]2025 Jul:142:156713. PMID: 40349422 -
Talanta
A robust polymetallic-coated sheathless interface with high acid and alkali resistance for coupling capillary electrophoresis with mass spectrometry. [Abstract]2025 Jan 1:282:127045. PMID: 39418980 -
ACS Omega
2023 Jun 14;8(25):22603-22612. PMID: 37387790
Solvant et solubilité
In Vitro:
H2O : 25 mg/mL (19.28 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (77.13 mM); Clear solution; Need ultrasonic
Pureté et documentation
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Fiche technique (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Manabe K, et al. Endothelium-dependent contractions induced by angiotensin I and angiotensin II in canine cerebral artery. J Pharmacol Exp Ther. 1989 Oct;251(1):317-20. [Content Brief]
[2]. Kawaguchi H, et al. Endothelin stimulates angiotensin I to angiotensin II conversion in cultured pulmonary artery endothelial cells. J Mol Cell Cardiol. 1990 Aug;22(8):839-42. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.7713 mL | 3.8566 mL | 7.7132 mL | 19.2830 mL |
| 5 mM | 0.1543 mL | 0.7713 mL | 1.5426 mL | 3.8566 mL | |
| 10 mM | 0.0771 mL | 0.3857 mL | 0.7713 mL | 1.9283 mL | |
| 15 mM | 0.0514 mL | 0.2571 mL | 0.5142 mL | 1.2855 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Angiotensin I (human, mouse, rat) Related Classifications
HY-P1032 Related Classifications
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