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Cat. No.: HY-17350

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Anitrazafen

(Synonyms: LY 122512)

Anitrazafen is a topically effective antiinflammatory agent.

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CAS No.: 63119-27-7
Formule: C₁₈H₁₇N₃O₂
Masse moléculaire:307.35

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Anitrazafen Chemical Structure

CAS No.: 63119-27-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Protocole
Pureté et documentation
Références
Calculators
Help & FAQs
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Bioz

Activité biologique

Description

Anitrazafen is a topically effective antiinflammatory agent.

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In Vivo

Anitrazafen is a topically effective antiinflammatory agent. The disposition of ¹⁴C in normal and in bile-duct cannulated rats after oral administration of a single dose of 25 mg/kg of [3-¹⁴C]Anitrazafen shows the drug to be well absorbed from the gastro-intestinal tract and biliary excretion to be the major route of elimination of drug and/or metabolites. Plasma concentrations of total ¹⁴C after subcutaneous administration of [3-¹⁴C]Anitrazafen in corn oil solution are about one half those found after oral administration^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 63119-27-7
Masse moléculaire 307.35
Formule C₁₈H₁₇N₃O₂
SMILES

CC1=NC(C2=CC=C(OC)C=C2)=C(C3=CC=C(OC)C=C3)N=N1
Synonyms

LY 122512
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocole

Animal Administration^[1]

Male albino rats (200 to 250 g) are fasted for 24 h before experiment. [3-¹⁴C]Anitrazafen (25 mg/kg) is administered orally to twelve rats. At specific times after dosing, three animals are killed by decapitation and samples of blood and appropriate tissues are removed. Duplicate weighed samples of blood and each tissue are removed for ¹⁴C assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (275 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sullivan HR, et al. Absorption and metabolism of anitrazafen, a topically effective anti-inflammatory agent, in the rat. Xenobiotica. 1981 Jan;11(1):9-22. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Chemical Information
Protocole
Pureté et documentation
Références

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Anitrazafen

Voir tous les produits spécifiques à Isoform Prostaglandin Receptor