AChE-IN-51
AChE-IN-51 (compound 8C) is an orally active, non-competitive inhibitor of AChE and BChE (IC50: 84 nM, 97 nM). It also inhibits MMP-2 and amyloid Aβ1-42 aggregates (IC50: 724 nM, 302 nM). AChE-IN-51 has low cytotoxicity and in silico predicted blood-brain barrier permeability. Can be used for research on diseases such as Alzheimer's disease (AD).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C23H21OP
- Masse moléculaire:344.39
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
|
AChE 84 nM (IC50) |
BChE 97 nM (IC50) |
MMP-2 724 nM (IC50) |
Chemical Information
-
Masse moléculaire 344.39
-
Formule C23H21OP
-
SMILES
CC(C(C=C)=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)