Atreleuton
Based on 1 Customer Validation
Atreleuton (ABT-761) is a selective, reversible, and orally bioavailable 5-Lipoxygenase (5-LO) inhibitor. Atreleuton (ABT-761) exhibits potent and selective inhibition of leukotriene formation. Atreleuton is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- Pureté: 99.9%
- CAS No.: 154355-76-7
- Formule: C16H15FN2O2S
- Masse moléculaire:318.37
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Immunology/Inflammation Compound Library
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Alkyne Compound Library
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Activité biologique
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5-LO |
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Cell Line
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Type | Value | Description | References |
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| RBL-1 | IC50 |
23 nM
Compound: 14, (A-85761, ABT-761)
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Compound was tested for in vitro inhibition against broken RBL-1.
Compound was tested for in vitro inhibition against broken RBL-1.
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[PMID: 8709092] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 154355-76-7
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Appearance Solid
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Masse moléculaire 318.37
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Formule C16H15FN2O2S
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Color White to off-white
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SMILES
O=C(N)N([C@H](C)C#CC1=CC=C(CC2=CC=C(F)C=C2)S1)O
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Synonyms
ABT-761; VIA-2291
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (268 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Atreleuton Related Classifications
HY-117853 Related Classifications
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