AUBE00
AUBE00 is an orally active, selective cyclic peptide pan-KRAS inhibitor. AUBE00 selectively binds to the OFF state of KRAS. AUBE00 exhibits anticancer activity against RAS wild-type colorectal cancer. The combination of AUBE00 with Cetuximab (HY-P9905) produces a synergistic antiproliferative effect.
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- CAS No.: 2874214-01-2
- Formule: C78H110F6N12O14
- Masse moléculaire:1553.77
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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K-RAS |
Chemical Information
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CAS No. 2874214-01-2
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Masse moléculaire 1553.77
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Formule C78H110F6N12O14
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SMILES
CN1C2(CCC2)C(N([C@@H](C3CCCC3)C(N([C@@H](CC(N([C@H](C(N[C@@](C(N4[C@](CCC4)([H])C(N([C@]5([H])C(N(CC/C=C\C5)[C@H](C(N(CC(N[C@H](C(N6[C@](C[C@H](C6)OCC)([H])C1=O)=O)CCC7=CC(OC)=C(C=C7)C(F)(F)F)=O)C)=O)CC8=CC=C(C=C8)C(F)(F)F)=O)C)=O)=O)([H])[C@@H](C)CC)=O)CCC)C)=O)C(N(C)C)=O)C)=O)C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AUBE00 Related Classifications
HY-183553 Related Classifications
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