Biotin-Thalidomide
Based on 1 Customer Validation
Biotin-Thalidomide is a biotin-conjugated Thalidomide (HY-14658) for binding to CRBN. Biotin-Thalidomide can be used to synthesize PROTAC .
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- Pureté : 99.45%
- CAS No.: 2230857-87-9
- Formule: C44H64N8O13S
- Masse moléculaire:945.09
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
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Cereblon |
Chemical Information
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CAS No. 2230857-87-9
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Appearance Solid
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Masse moléculaire 945.09
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Formule C44H64N8O13S
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Color Off-white to yellow
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SMILES
O=C1C2=C(OCC(NCCCCNC(CCCC(NCCCOCCOCCOCCCNC(CCCC[C@H]3[C@]4([H])[C@](NC(N4)=O)([H])CS3)=O)=O)=O)=O)C=CC=C2C(N1C5C(NC(CC5)=O)=O)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
Methanol : 125 mg/mL (132.26 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol | 1 mM | 1.0581 mL | 5.2905 mL | 10.5810 mL | 26.4525 mL |
| 5 mM | 0.2116 mL | 1.0581 mL | 2.1162 mL | 5.2905 mL | |
| 10 mM | 0.1058 mL | 0.5291 mL | 1.0581 mL | 2.6453 mL | |
| 15 mM | 0.0705 mL | 0.3527 mL | 0.7054 mL | 1.7635 mL | |
| 20 mM | 0.0529 mL | 0.2645 mL | 0.5291 mL | 1.3226 mL | |
| 25 mM | 0.0423 mL | 0.2116 mL | 0.4232 mL | 1.0581 mL | |
| 30 mM | 0.0353 mL | 0.1764 mL | 0.3527 mL | 0.8818 mL | |
| 40 mM | 0.0265 mL | 0.1323 mL | 0.2645 mL | 0.6613 mL | |
| 50 mM | 0.0212 mL | 0.1058 mL | 0.2116 mL | 0.5291 mL | |
| 60 mM | 0.0176 mL | 0.0882 mL | 0.1764 mL | 0.4409 mL | |
| 80 mM | 0.0132 mL | 0.0661 mL | 0.1323 mL | 0.3307 mL | |
| 100 mM | 0.0106 mL | 0.0529 mL | 0.1058 mL | 0.2645 mL |
Biotin-Thalidomide Related Classifications
HY-145152 Related Classifications
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