BRD-7880
BRD-7880 is a potent and highly specific inhibitor of Aurora Kinase B (AURKB) and Aurora Kinase C (AURKC), with IC50 values of 7 nM and 12 nM, respectively.
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- CAS No.: 1456542-69-0
- Formule: C32H38N4O7
- Masse moléculaire:590.67
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform Aurora Kinase
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Activité biologique
Description
IC50 & Target
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Aurora B 7 nM (IC50) |
Aurora C 12 nM (IC50) |
Aurora A 2153 nM (IC50) |
Chemical Information
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CAS No. 1456542-69-0
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Masse moléculaire 590.67
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Formule C32H38N4O7
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SMILES
O=C1C2=CC(NC(NC3=CC=C(C=C3)OC)=O)=CC=C2O[C@H]([C@H](CN1[C@@H](C)CO)C)CN(C)CC4=CC=C(OCO5)C5=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)