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Cibisatamab

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Based on 2 publication(s) in Google Scholar

Cibisatamab, a T cell bispecific antibody, binds Carcino-Embryonic Antigen (CEA) on cancer cells and CD3 on T cells. Cibisatamab triggers T cell killing of cancer cell lines expressing moderate to high levels of CEA at the cell surface. Cibisatamab can be used for colorectal cancer research.

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  • Pureté: 99.75%
  • CAS No.: 1855925-27-7
  • Masse moléculaire:171 kDa
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cibisatamab
  • Experimental Validation Results for Cibisatamab
  • Cibisatamab Chemical Structure
    Cibisatamab Chemical Structure
CAS No.: 1855925-27-7
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  • 1/16

    IgG1-kappa/lambda with domain crossover, trivalent

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells with Cibisatamab (HY-P99011, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Cibisatamab Chemical Structure
    1/16
  • Cibisatamab
  • Flow cytometric analysis of 1X106 Jurkat cells with Cibisatamab (HY-P99011, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • IgG1-kappa/lambda with domain crossover, trivalent