Cyanidin
Based on 5 publication(s) in Google Scholar
Cyanidin is an orally active antioxidant and enzyme inhibitor. Cyanidin has IC50 values of 90 μM and 60 μM against PGHS-1 and PGHS-2, respectively. Cyanidin exhibits excellent antioxidant and anti-inflammatory activities, scavenges free radicals, inhibits lipid peroxidation, and protects DNA from cleavage. Cyanidin can be used in the research of inflammatory diseases.
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- CAS No.: 13306-05-3
- Formule: C15H11O6+
- Masse moléculaire:287.24
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Publications Citing Use of MedChemExpress (MCE) Cyanidin
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Activité biologique
Description
In Vitro
Cyanidin (2 μM; 21 min) inhibits lipid peroxidation in a liposomal model system with 57% inhibition at 2 μM, showing antioxidant activity comparable to commercial antioxidants BHA and BHT and superior to vitamin E[2].
Cyanidin (5-30 μM) scavenges DPPH radicals in a concentration-dependent manner[3].
Cyanidin (0.1-1 μM) scavenges O2− radicals in a concentration-dependent manner[3].
Cyanidin (100-400 μM) protects DNA from H2O2-induced damage[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 13306-05-3
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Masse moléculaire 287.24
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Formule C15H11O6+
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SMILES
OC1=CC2=[O+]C(C3=CC=C(O)C(O)=C3)=C(O)C=C2C(O)=C1
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (5)
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Journal Impact Factor
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Most Recent
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Food Res Int
Slow starch digestion in the rice cooked with adzuki bean: Contribution of procyanidins and the oxidation products. [Abstract]2019 May:119:187-195. PMID: 30884648 -
Int Immunopharmacol
IL-17A/IL-17RA interaction blockade sensitizes synovial macrophages to efferocytosis and PD-L1 signaling via rewiring STAT-3/ADAM17/MERTK axis in rheumatoid arthritis animal model. [Abstract]2024 Jul 30:136:112343. PMID: 38810305 -
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Hum Cell
Long noncoding RNA XIST modulates microRNA-135/CREB1 axis to influence osteogenic differentiation of osteoblast-like cells in mice with tibial fracture healing. [Abstract]2022 Jan;35(1):133-149. PMID: 34635983 -
Pureté et documentation
Références
[1]. Noda Y, et al. Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin. J Agric Food Chem. 2002;50(1):166-171. [Content Brief]
[2]. Wang H, et al. Antioxidant and antiinflammatory activities of anthocyanins and their aglycon, cyanidin, from tart cherries. J Nat Prod. 1999;62(2):294-296. [Content Brief]
[3]. Acquaviva R, et al. Cyanidin and cyanidin 3-O-beta-D -glucoside as DNA cleavage protectors and antioxidants. Cell Biol Toxicol. 2003 Aug;19(4):243-52. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cyanidin Related Classifications
HY-N0499A Related Classifications
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