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Cat. No.: HY-119054

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DNMT1-IN-4

DNMT1-IN-4 is a potent non-nucleoside DNA methyltransferase 1 (DNMT1) inhibitor with an IC₅₀ value of 2.5 µM and selectivity towards other AdoMet-dependent protein methyltransferases. DNMT1-IN-4 significantly inhibits cancer cell proliferation.

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CAS No.: 889797-65-3
Formule: C₂₅H₂₃Cl₂N₃O
Masse moléculaire:452.38

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

DNMT1-IN-4 Chemical Structure

CAS No.: 889797-65-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Voir tous les produits spécifiques à Isoform DNA Methyltransferase :

Chemical Information

CAS No. 889797-65-3
Masse moléculaire 452.38
Formule C₂₅H₂₃Cl₂N₃O
SMILES

OC(CNCCC1=CNC2=C1C=CC=C2)CN3C4=C(C=C(C=C4)Cl)C5=C3C=CC(Cl)=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chen S, ET AL. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57(21):9028-41. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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DNMT1-IN-4

Voir tous les produits spécifiques à Isoform DNA Methyltransferase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

DNMT1-IN-4 Related Classifications

HY-119054 Related Classifications