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Cat. No.: HY-145569

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Fipravirimat

(Synonyms: GSK3640254)

Fipravirimat is a potent HIV-1 inhibitor. Fipravirimat has the potential for HIV and AIDS research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1818867-24-1
Formule: C₄₃H₆₇FN₂O₄S
Masse moléculaire:727.07

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Fipravirimat Chemical Structure

CAS No.: 1818867-24-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Fipravirimat is a potent HIV-1 inhibitor. Fipravirimat has the potential for HIV and AIDS research^[1].

IC₅₀ & Target^[1]

HIV-1

Voir tous les produits spécifiques à Isoform HIV :

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	CC₅₀	13.3 μM Compound: 41	Cytotoxicity in human MT2 cells assessed as reduction in cell viability Cytotoxicity in human MT2 cells assessed as reduction in cell viability	[PMID: 36044257]
MT2	CC₅₀	13.3 μM Compound: 5	Cytotoxicity against human MT2 cells assessed as reduction in cell viability Cytotoxicity against human MT2 cells assessed as reduction in cell viability	[PMID: 36441509]
MT2	CC₅₀	15.6 μM Compound: 4; GSK3640254	Cytotoxicity against human MT2 cells assessed as reduction in cell viability Cytotoxicity against human MT2 cells assessed as reduction in cell viability	[PMID: 36441509]
MT2	CC₅₀	15.6 μM Compound: 9; GSK3640254	Cytotoxicity in human MT2 cells assessed as reduction in cell viability Cytotoxicity in human MT2 cells assessed as reduction in cell viability	[PMID: 36044257]

Chemical Information

CAS No. 1818867-24-1
Masse moléculaire 727.07
Formule C₄₃H₆₇FN₂O₄S
SMILES

O=S(CCN1CCN[C@]23[C@@]([C@@H](CC3)C(C)=C)([H])[C@]4([H])[C@@](CC2)([C@]5([C@]([C@@]6([C@@](C(C)(C(C7=CC[C@](C(O)=O)(CF)CC7)=CC6)C)([H])CC5)C)([H])CC4)C)C)(CC1)=O
Synonyms

GSK3640254
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Jie Chen, et al. C-3 and c-17 modified triterpenoids as hiv-1 inhibitors. WO2017134596A1.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Fipravirimat

Voir tous les produits spécifiques à Isoform HIV

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Fipravirimat Related Classifications

HY-145569 Related Classifications