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FR104

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Based on 2 publication(s) in Google Scholar

FR104 is a humanized antibody expressed in CHO cells that targets CD28. FR104 comprises a huIgG2 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.08 kDa. The isotype control for FR104 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

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  • Pureté: 97.26%
  • Masse moléculaire:145.08 kDa
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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for FR104
  • Experimental Validation Results for FR104
  • FR104 Chemical Structure
    FR104 Chemical Structure
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  • 1/16

    Immobilized CD28 Protein, Human can bind FR104. The EC50 for this effect is 8.381 ng/mL.

  • 1/16

    Flow cytometric analysis of 106 Jurkat cells with FR104 (HY-P990587, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor® 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control.

  • FR104 Chemical Structure
    1/16
  • FR104
  • Immobilized CD28 Protein, Human can bind FR104. The EC50 for this effect is 8.381 ng/mL.
  • Flow cytometric analysis of 106 Jurkat cells with FR104 (HY-P990587, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor® 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG2 kappa (HY-P99002, blue) was used as the isotype control.