HU 331
HU 331 (HU 331) is a highly specific Topoisomerase II inhibitor with anticancer activity. HU 331 has shown promising inhibitory effects on human cancer cell lines in vitro and human tumor xenografts in nude mice in vivo.
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- CAS No.: 137252-25-6
- Formule: C21H28O3
- Masse moléculaire:328.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
[1]|
Topoisomerase II |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | EC50 |
10.5 μM
Compound: 2; CBDQ, HU-313
|
Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6 hrs by dual luciferase reporter gene assay
Agonist activity at GAL4-tagged PPARgamma (unknown origin) transiently expressed in HEK293T cells co-transfected with GAL4-tagged luc incubated for 6 hrs by dual luciferase reporter gene assay
|
[PMID: 32315173] |
Chemical Information
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CAS No. 137252-25-6
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Masse moléculaire 328.45
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Formule C21H28O3
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SMILES
CC([C@H]1[C@H](C2=C(C(C(CCCCC)=CC2=O)=O)O)C=C(CC1)C)=C
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Synonyms
VCE 004
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)