Ixazomib-d7
Ixazomib-d7 is the deuterium labeled Ixazomib (HY-10453). Ixazomib (MLN2238) is a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM).
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- CAS No.: 2177240-89-8
- Formule: C14H12D7BCl2N2O4
- Masse moléculaire:368.07
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2177240-89-8
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Unlabeled Cas 1072833-77-2
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Masse moléculaire 368.07
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Formule C14H12D7BCl2N2O4
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SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C[C@@H](B(O)O)NC(CNC(C1=C(C=CC(Cl)=C1)Cl)=O)=O
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Synonyms
MLN2238-d7
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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