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Cat. No.: HY-123575

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LY 245769

LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC₅₀s of 4 μM.

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CAS No.: 127345-02-2
Formule: C₂₅H₃₃F₃N₈OS
Masse moléculaire:550.64

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

LY 245769 Chemical Structure

CAS No.: 127345-02-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC₅₀s of 4 μM^[1].

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Chemical Information

CAS No. 127345-02-2
Masse moléculaire 550.64
Formule C₂₅H₃₃F₃N₈OS
SMILES

O[C@@H](C1=CC=CC(C2=NN=NN2)=C1)[C@@H](/C=C/C=C\CCCCCCCCC(F)(F)F)SCCC3=NN=NN3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. G Jedlitschky, et al. Inhibition of leukotriene omega-oxidation by omega-trifluoro analogs of leukotrienes. Arch Biochem Biophys. 1990 Nov 1;282(2):333-9. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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LY 245769

Voir tous les produits spécifiques à Isoform Leukotriene Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

LY 245769 Related Classifications

HY-123575 Related Classifications