MRS3558
MRS3558 is a potent and selective A3AR agonist, with Ki values of 0.6 nM for humans and 0.9 nM for rats, making it suitable for research in the fields of neuropathic pain and anesthesia.
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- CAS No.: 793695-40-6
- Formule: C20H20Cl2N6O3
- Masse moléculaire:463.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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hA2AAR 0.6 nM (Ki) |
rA2A 0.9 nM (Ki) |
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Cell Line
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Type | Value | Description | References |
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| HEK293 | IC50 |
3.26 μM
Compound: 35
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Antagonist activity at human 5-HT2BR expressed in Flp-In HEK cells assessed as inhibition of 5-HT-induced calcium mobilization preincubated for 5 to 10 mins followed 5-HT addition by Fluo-4 dye based FLIPR assay
Antagonist activity at human 5-HT2BR expressed in Flp-In HEK cells assessed as inhibition of 5-HT-induced calcium mobilization preincubated for 5 to 10 mins followed 5-HT addition by Fluo-4 dye based FLIPR assay
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[PMID: 27933810] |
Chemical Information
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CAS No. 793695-40-6
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Masse moléculaire 463.32
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Formule C20H20Cl2N6O3
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SMILES
CNC([C@]12[C@@H]([C@@H](N3C4=NC(Cl)=NC(NCC5=CC(Cl)=CC=C5)=C4N=C3)[C@H](O)[C@@H]2O)C1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MRS3558 Related Classifications
HY-122231 Related Classifications
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