country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N4329

Copy Link Print Information

Nidulalin A

Nidulalin A is a DNA topoisomerase II inhibitor with an IC₅₀ of 2.2 μM. Nidulalin A has an IC₅₀ of 172 μM for DNA topoisomerase I. Nidulalin A has certain cytotoxicity.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 162901-86-2
Formule: C₁₆H₁₄O₆
Masse moléculaire:302.28

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Nidulalin A Chemical Structure

CAS No.: 162901-86-2

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Nidulalin A is a DNA topoisomerase II inhibitor with an IC₅₀ of 2.2 μM. Nidulalin A has an IC₅₀ of 172 μM for DNA topoisomerase I. Nidulalin A has certain cytotoxicity^[1].

Voir tous les produits spécifiques à Isoform Topoisomerase :

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	0.14 μM Compound: 1 (Nidulalin A)	In vitro cytotoxic activity against human cancer cell line HCT116 by using MTT assay In vitro cytotoxic activity against human cancer cell line HCT116 by using MTT assay	[PMID: 10509910]
K562	IC₅₀	0.32 μM Compound: 1 (Nidulalin A)	In vitro cytotoxic activity against human cancer cell line K562 by using MTT assay In vitro cytotoxic activity against human cancer cell line K562 by using MTT assay	[PMID: 10509910]
P388	IC₅₀	0.024 μM Compound: 1 (Nidulalin A)	In vitro cytotoxic activity against murine cancer cell line P388 by using MTT assay In vitro cytotoxic activity against murine cancer cell line P388 by using MTT assay	[PMID: 10509910]

Chemical Information

CAS No. 162901-86-2
Masse moléculaire 302.28
Formule C₁₆H₁₄O₆
SMILES

COC([C@]12C(C(C3=C(O)C=C(C)C=C3O2)=O)=CC=C[C@H]1O)=O
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Penicillium sp. AJ117292
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Sato S, et al. Inhibition of DNA topoisomerases by nidulalin A derivatives. Biol Pharm Bull. 2000 Apr;23(4):511-2. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis

Amount: USD 0.00

Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

Nidulalin A

Voir tous les produits spécifiques à Isoform Topoisomerase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Nidulalin A Related Classifications

HY-N4329 Related Classifications