NNRT-IN-9
NNRT-IN-9 (Compound EG28) is a non-nucleoside reverse transcriptase (NNRT) inhibitor. NNRT-IN-9 has potent antiviral and anti-resistance activity against wild-type (WT) HIV-1 and various clinically relevant mutations (E138K and K103N + Y181C) with EC50s of 55, 67 and 3910 nM, respectively. NNRT-IN-9 can be used for acquired immune deficiency syndrome (AIDS) research.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C22H16N6O
- Masse moléculaire:380.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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HIV-1 (WT) 55 nM (EC50) |
HIV-1 (E138K) 67 nM (EC50) |
HIV-1 (K103N+Y181C) 3910 nM (EC50) |
Chemical Information
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Masse moléculaire 380.40
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Formule C22H16N6O
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SMILES
N#CC1=CC(N2C(N(CC3=CC=CC=C32)CC4=NNC5=NC=CC=C45)=O)=CC=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NNRT-IN-9 Related Classifications
HY-174303 Related Classifications
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