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REGN-7257

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REGN-7257 is a humanized monoclonal antibody targeting IL2RG. REGN-7257 blocks the signal transduction induced by common gamma chain (γc) cytokines via the IL2RG chain of the γc cytokine receptor complex. REGN-7257 is applicable for research on immune-mediated diseases and T cell-mediated diseases. Its corresponding isotype control is Human IgG4 kappa, Isotype Control (HY-P99003).

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  • Pureté: 95.34%
  • Masse moléculaire:145.41 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for REGN-7257
  • Experimental Validation Results for REGN-7257
  • REGN-7257 Chemical Structure
    REGN-7257 Chemical Structure
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REGN-7257 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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  • 1/16

    Immobilized Human IL-2 R gamma/CD132 Protein, His Tag can bind REGN-7257. The EC50 for this effect is 116.4 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 SH-SY5Y cells labeling IL2RG with REGN-7257 (HY-P991201, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control.

  • REGN-7257 Chemical Structure
    1/16
  • REGN-7257
  • Immobilized Human IL-2 R gamma/CD132 Protein, His Tag can bind REGN-7257. The EC50 for this effect is 116.4 ng/mL.
  • Flow cytometric analysis of 1X106 SH-SY5Y cells labeling IL2RG with REGN-7257 (HY-P991201, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 for an hour at 4℃. AF488-conjugated Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa Isotype Control (HY-P99003, blue) was used as the isotype control.