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Cat. No.: HY-162118

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RGH-122

RGH-122 (compound 43) is an orally active, potent, selective, and hV1a receptor antagonist with K_i value of 0.3 nM and IC₅₀ of 0.9 nM. RGH-122 showes microsomal stability with CL_int value of 13/28/25 μL/min/mg.

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CAS No.: 2355304-05-9
Formule: C₂₄H₂₅ClN₄O₃
Masse moléculaire:452.93

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

RGH-122 Chemical Structure

CAS No.: 2355304-05-9

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

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Chemical Information

CAS No. 2355304-05-9
Masse moléculaire 452.93
Formule C₂₄H₂₅ClN₄O₃
SMILES

ClC1=CC=[C@]2[N@]3C([C@H](CC4)CC[C@@H]4OC5=NC=CC=C5)=NN=C3CC6(OCCO6)CC2=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Baska F, et al. Discovery and Characterization of RGH-122, a Potent, Selective, and Orally Bioavailable V1a Receptor Antagonist. J Med Chem. 2024 Jan 11;67(1):643-673. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RGH-122

Voir tous les produits spécifiques à Isoform Vasopressin Receptor

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RGH-122 Related Classifications

HY-162118 Related Classifications

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