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Cat. No.: HY-156958

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S-72

S-72 inhibits tubulin polymerization and further triggers mitosis-phase cell cycle arrest and cell apoptosis, in addition to suppressing STAT3 signaling.

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CAS No.: 2446799-14-8
Formule: C₂₀H₂₂N₄O₃S
Masse moléculaire:398.48

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

S-72 Chemical Structure

CAS No.: 2446799-14-8

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Description

S-72 inhibits tubulin polymerization and further triggers mitosis-phase cell cycle arrest and cell apoptosis, in addition to suppressing STAT3 signaling^[1].

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Chemical Information

CAS No. 2446799-14-8
Masse moléculaire 398.48
Formule C₂₀H₂₂N₄O₃S
SMILES

O=C(C1=CC=C(C)C(NS(=O)(C2=CC=C(C)C=C2)=O)=C1)NCC3=CN(C)N=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhenyan Hou, et al. S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance via Inactivation of the STING Pathway in Breast Cancer. Pharmaceuticals (Basel). 2023 May 15;16(5):749. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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S-72

PTUPB

(+)-Erinacin A

Isogarcinol

PDIC-NN

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S-72

PTUPB

(+)-Erinacin A

Isogarcinol

PDIC-NN

Voir tous les produits spécifiques à Isoform STAT

Activité biologique

Chemical Information

Pureté et documentation

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S-72 Related Classifications

HY-156958 Related Classifications