2438 Results for "

decrease

" in MedChemExpress (MCE) Product Catalog:
Products (2438)

2438 Results for "decrease" in MCE Product Catalog:

Cat. No.: HY-110020
CAS No.: 851320-29-1
Target:  

Cannabinoid Receptor

Domaines de recherche:  

Metabolic Disease

rel-O-2050 (Compound O-2050) is a neutral cannabinoid CB1 receptor antagonist. rel-O-2050 also decreases food intake in mice .
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Cat. No.: HY-111308
CAS No.: 847554-50-1
Domaines de recherche:  

Neurological Disease

RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration .
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Cat. No.: HY-117805
CAS No.: 177847-28-8
Target:  

Angiotensin Receptor

Domaines de recherche:  

Cardiovascular Disease

UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow .
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Cat. No.: HY-119926
CAS No.: 15358-48-2
Synonyms: Hydroxylupanine
Target:  

Integrin

Domaines de recherche:  

Cardiovascular Disease Neurological Disease

13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .
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Cat. No.: HY-119926A
CAS No.: 6809-89-8
Synonyms: Hydroxylupanine hydrochloride
13-Hydroxylupanine Hydroxylupanine is the typical alkaloid profile of sweet lupins. 13-Hydroxylupanine Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .
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Cat. No.: HY-122101
CAS No.: 17392-79-9
Target:  

JAK Apoptosis

Domaines de recherche:  

Cancer

NSC114792 is a selective JAK3 inhibitor. NSC114792 induces apoptosis. NSC114792 decreases the protein expression of p-JAK3 and p-STAT5 .
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Cat. No.: HY-126852
CAS No.: 163217-70-7
Synonyms: P-Hydroxyatorvastatin lactone; 4-ATL
Target:  

Drug Metabolite

Domaines de recherche:  

Metabolic Disease Inflammation/Immunology

4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids .
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Cat. No.: HY-136676
CAS No.: 122088-76-0
Target:  

Renin

Domaines de recherche:  

Cancer

Cgp 38560 methanesulfonate is a well-tolerated renin inhibitor. Cgp 38560 methanesulfonate caused a dose-dependent decrease in angiotensin II and plasma renin activity, and a dose-dependent increase in active renin.
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Cat. No.: HY-147327
CAS No.: 26367-45-3
Target:  

Drug Metabolite

Domaines de recherche:  

Cancer

N-Formylsarcolysine has antitumor activity, and inhibits leukemia by increasing the Hb and erythrocyte levels and decreasing the number of leukocytes. N-Formylsarcolysine also involves in glioblastoma and other diseases research .
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Cat. No.: HY-158329
CAS No.: 561022-65-9
Pureté:  98.40%
Synonyms: N-Alloc doxorubicin
Domaines de recherche:  

Cancer

Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth .
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Cat. No.: HY-163279
CAS No.: 885902-66-9
Target:  

Glycosidase

Domaines de recherche:  

Others

Fluopipamine is an antagonist for Cellulose Synthase 1 (CESA1) with an IC50 of 0.78 μM. Fluopipamine leads a decrease in glucose uptake into cellulose and hyperaccumulation of CESAs at the PM in etiolated Arabidopsis seedlings .
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Cat. No.: HY-179114
CAS No.: 1211788-57-6
Domaines de recherche:  

Others

VU0519975 is a raft destabilizing compound. VU0519975 reduces PMP22 raft partitioning and destabilizes ordered domains. VU0519975 significantly decreases the fraction of phase separated GPMVs .
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Cat. No.: HY-180958
CAS No.: 3104316-26-6
Target:  

PROTACs

Domaines de recherche:  

Others

Chlorohexane-PEG-clozapine is a HaloTag PROTAC degrader based on Clozapine (HY-14539). Chlorohexane-PEG-clozapine leads to a significant decrease in the luminescence intensity and protein level of Halo-Eluc .
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Cat. No.: HY-B0606A
CAS No.: 59985-21-6
Synonyms: INS365 free base
Diquafosol (INS365 free base) is a potent P2Y2 agonist. Diquafosol nhibits apoptosis and decreases ROS generation. Diquafosol has the potential for the research of dry eye .
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Cat. No.: HY-N7646
CAS No.: 143601-09-6
Curculigoside B, a phenolic glycoside isolated from Curculigo orchioides, enhances the osteoblast proliferation, decreases the area of bone resorption pit, osteoclastic formation and TRAP activity. Antiosteoporotic and antioxidative activities .
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Cat. No.: HY-P3637
CAS No.: 2640019-27-6
Target:  

Inhibitory Antibodies

Domaines de recherche:  

Inflammation/Immunology

AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG promotes bone-ossification. AVSEHQLLHDKGKSIQDLRRRFFLHHLI-{Aib}-EIHTAYRFGG can be used in the research of diseases or disorders related to osteogenic defects or bone mineral density (BMD) decreasing, such as osteoporosis .
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Cat. No.: HY-P99627
CAS No.: 1708936-80-4
Synonyms: NV-02; PG110; ABT-110

Target:  

Trk Receptor

Domaines de recherche:  

Inflammation/Immunology

Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats .
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Cat. No.: HY-116953
CAS No.: 98049-69-5
Synonyms: LXB4
Target:  

Endogenous Metabolite

Domaines de recherche:  

Inflammation/Immunology

Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .
The product specifications provided below refer solely to the active content of Lipoxin B4.
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Cat. No.: HY-120152
CAS No.: 1449765-82-5
SLP7111228 is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
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Cat. No.: HY-120152A
CAS No.: 1449768-48-2
Pureté:  98.0%
SLP7111228 hydrochloride is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 hydrochloride selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 hydrochloride decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 hydrochloride alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 hydrochloride can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
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