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Cat. No.: HY-187907

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Surbinsertib

Name: Surbinsertib
Brand: MedChemExpress
SKU: HY-187907
Availability: PreOrder

(Synonyms: SGR-3515)

Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 3038330-83-2
Formule: C₃₀H₄₀N₈O₂S
Masse moléculaire:576.76

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (285 KB)

Surbinsertib Chemical Structure

CAS No.: 3038330-83-2

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Activité biologique
- Description
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research^[1]^[2].

Voir tous les produits spécifiques à Isoform Wee1 :

PKMYT1

In Vitro

Both Wee1 and Myt1 are CDK-inhibitory kinases. Wee1 primarily phosphorylates CDK1‑Tyr15, while Myt1 phosphorylates both CDK1‑Tyr15 and Thr14. The two kinases act synergistically to inhibit CDK1 activity and regulate the G2/M cell cycle transition.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 3038330-83-2
Masse moléculaire 576.76
Formule C₃₀H₄₀N₈O₂S
SMILES

C[C@]12[C@](CC(C)(OC2)C)([H])N(C3=CC=CC(N=S(C)(C)=O)=N3)C4=NC(NC5=CC=C(N6CCN(CC6)C)C=C5)=NC=C41
Synonyms

SGR-3515
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (285 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. WHO Drug Information, Vol. 40, No. 2, 2026

[2]. Shaoxian Sun, et al, Abstract 3025: Optimization of therapeutic index of SGR-3515, a first-in-class Wee1/Myt1 inhibitor through intermittent dosing for monotherapy and combination with chemotherapy in xenograft tumor models. Cancer Res 15 April 2025; 85.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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