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Cat. No.: HY-106090

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Teloxantrone

Name: Teloxantrone
Brand: MedChemExpress
SKU: HY-106090
Availability: PreOrder

(Synonyms: CI-937; DUP 937)

Teloxantrone (CI-937; DUP 937) is a DNA synthesis inhibitor (IC₅₀: 0.33 μM). Teloxantrone has antitumor activity and can be used in colorectal cancer research.

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CAS No.: 91441-48-4
Formule: C₂₁H₂₅N₅O₄
Masse moléculaire:411.45

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Teloxantrone Chemical Structure

CAS No.: 91441-48-4

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Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Teloxantrone (CI-937; DUP 937) is a DNA synthesis inhibitor (IC₅₀: 0.33 μM). Teloxantrone has antitumor activity and can be used in colorectal cancer research^[1]^[2].

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Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC₅₀	1.4 x 10^-7M Compound: 74	Tested in vitro against murine L1210 leukemia. Tested in vitro against murine L1210 leukemia.	[PMID: 3806589]
L1210	IC₅₀	1.40E-07 M Compound: 74	Tested in vitro against murine L1210 leukemia. Tested in vitro against murine L1210 leukemia.	[PMID: 3806589]

Chemical Information

CAS No. 91441-48-4
Masse moléculaire 411.45
Formule C₂₁H₂₅N₅O₄
SMILES

CNCCNC1=C2C3=C(C=C1)N(CCNCCO)N=C3C4=C(C(O)=CC=C4O)C2=O
Synonyms

CI-937; DUP 937
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Fry DW, et al. In vitro DNA strand scission and inhibition of nucleic acid synthesis in L1210 leukemia cells by a new class of DNA complexers, the anthra[1,9-cd]pyrazol-6(2H)-ones (anthrapyrazoles). Biochem Pharmacol. 1985 Oct 1;34(19):3499-508. [Content Brief]

[2]. Maroun JA, et al. Phase II study on DuP 937 (Teloxantrone) in colorectal carcinoma. A Canadian National Cancer Institute Clinical Trial Group study. Invest New Drugs. 1993 May-Aug;11(2-3):235-7. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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