Thioredoxin reductase
Based on 1 Customer Validation
Thioredoxin reductase (TrxR) is a selenocysteine-containing NADPH-dependent disulfide oxidoreductase derived from rat liver that utilizes NADPH to reduce oxidized thioredoxin. Thioredoxin reductase can utilize the reducing capacity of human erythrocytes to study the uptake and reduction of α-Lipoic Acid (HY-N0492), and can also be used to investigate the activation mechanism of transglutaminase 2 (TG2) in the extracellular matrix using thioredoxin.
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- CAS No.: 9074-14-0
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Thioredoxin reductase (TrxR) is rapidly inactivated in serum by NADPH or NADPH-regenerating systems, and in the serum of H22 hepatoma-bearing mice, endogenous electrophilic compounds PpIX and 4-HNE are increased[1].
Thioredoxin reductase (from rat liver) can utilize the reducing capacity of human erythrocytes to study the uptake and reduction of α-lipoic acid[2].
Thioredoxin reductase (from rat liver) is used to study the activation mechanism of transglutaminase 2 (TG2) in the extracellular matrix using thioredoxin[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9074-14-0
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Thioredoxin reductase]
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Synonyms
TrxR
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
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Fiche technique (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thioredoxin reductase Related Classifications
HY-P2759 Related Classifications
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