1637532-83-2
Chemical Structure
PM-81I
- CAS No.: 1637532-83-2
- Formula:C43H58F2N3O10P
- Molecular Weight:845.91
IUPAC Name: ((((4-((E)-4-(((S)-3,3-dimethyl-1-oxo-1-((S)-2-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)pyrrolidin-1-yl)butan-2-yl)amino)-4-oxobut-2-en-2-yl)phenyl)difluoromethyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
InChIKey: RWUNEWNLTKQICG-KDRQYZKKSA-N
SMILES: O=C(N1CC2=CC=CC=C2CC1)[C@H]3N(CCC3)C([C@H](C(C)(C)C)NC(/C=C(C4=CC=C(C=C4)C(F)(F)P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)\C)=O)=O
Biological Activity: PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels. PM-81I can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1] sup>.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PM-81I | 99.91% | PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels. PM-81I can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer sup>. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.67
HY-148092PM-43I -
Similarity Score 0.49
HY-169182AK-068 -
Similarity Score 0.49
HY-401505TD1092 intermediate-1 -
Similarity Score 0.46
HY-135997IAP ligand 12 -
Similarity Score 0.45
HY-169180AK-068-OH -
Similarity Score 0.45
HY-P1126Dolastatin 15 -
Similarity Score 0.44
HY-138964TC-PTP-IN-1 -
Similarity Score 0.44
HY-120434AEG40826 -
Similarity Score 0.44
HY-P2096Hexapeptide-11 -
Explore the MedChemAI to find more analogs