IAP ligand 12
IAP ligand 12 is a IAP recruiting molecule and also a building block for the synthesis of IAP-CRBN heterodimer-targeted chimeric degrading molecules (PROTACs). IAP ligand 12 can be used to synthesize the IAP degrader TD-1092 (HY-151966).
For research use only. We do not sell to patients.
- CAS No.: 3037417-28-7
- Formula: C30H40N4O4
- Molecular Weight:520.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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cIAP1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | GI50 |
>500 μM
Compound: 1
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Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
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[PMID: 36410083] |
Chemical Information
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CAS No. 3037417-28-7
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Molecular Weight 520.66
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Formula C30H40N4O4
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SMILES
O=C(N[C@@H]1CCCC2=C1C=CC=C2)[C@H]3N(C([C@@H](NC([C@H](C)NC)=O)C(C)(C)C)=O)CC4=C(C=CC(O)=C4)C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IAP ligand 12 Related Classifications
HY-135997 Related Classifications
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