IAP ligand 12
IAP ligand 12 is a IAP recruiting molecule and also a building block for the synthesis of IAP-CRBN heterodimer-targeted chimeric degrading molecules (PROTACs). IAP ligand 12 can be used to synthesize the IAP degrader TD-1092 (HY-151966).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 3037417-28-7
- 화학식: C30H40N4O4
- 분자량:520.66
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
IC50 & Target
|
cIAP1 |
cIAP2 |
XIAP |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | GI50 |
500 μM
Compound: 1
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Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
|
[PMID: 36410083] |
| MCF7 | GI50 |
>500 μM
Compound: 1
|
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo luminescent assay
|
[PMID: 36410083] |
Chemical Information
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CAS No. 3037417-28-7
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분자량 520.66
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화학식 C30H40N4O4
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SMILES
O=C(N[C@@H]1CCCC2=C1C=CC=C2)[C@H]3N(C([C@@H](NC([C@H](C)NC)=O)C(C)(C)C)=O)CC4=C(C=CC(O)=C4)C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IAP ligand 12 Related Classifications
HY-135997 Related Classifications
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