2353-45-9
2353-45-9
Chemical Structure
Fast Green FCF
Synonym(s): FD&C Green No. 3; Food green 3; C.I. 42053
- No. CAS: 2353-45-9
- Formula:C37H34N2Na2O10S3
- Molecular Weight:808.85
IUPAC Name: sodium 2-((E)-(4-(ethyl(3-sulfonatobenzyl)amino)phenyl)((E)-4-(ethyl(3-sulfonatobenzyl)iminio)cyclohexa-2,5-dien-1-ylidene)methyl)-5-hydroxybenzenesulfonate
InChIKey: RZSYLLSAWYUBPE-UHFFFAOYSA-L
SMILES: O=S(C1=CC(C/[N+](CC)=C2C=C/C(C=C/2)=C(C3=CC=C(N(CC)CC4=CC=CC(S(=O)(O[Na])=O)=C4)C=C3)\C5=CC=C(O)C=C5S(=O)(O[Na])=O)=CC=C1)([O-])=O
Biological Activity: Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF inhibits α-synuclein aggregation, as well as Aβ and P2X4 receptor, and TLR4/Myd88/NF-κB. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF improves cognitive impairment, depression, relieves pain allergies, and promotes reproductive function[1][2][3][4][5][6][7][8][9].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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Fast Green FCF | 98.45% | Fast Green FCF is a sea green triarylmethane food dye, with absorption maximum ranging from 622 to 626 nm. Fast Green FCF inhibits α-synuclein aggregation, as well as Aβ and P2X4 receptor, and TLR4/Myd88/NF-κB. Fast Green FCF is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF improves cognitive impairment, depression, relieves pain allergies, and promotes reproductive function. | ||||||||||||||||||||
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Light green SF yellowish | 75.0% | Light green SF yellowish (Acid Green 5) is a water-soluble triarylmethane dye. Light green SF yellowish serves as a histological stain that selectively labels mitochondria, collagen, and cartilage, while being an essential component of Papanicolaou staining. Light green SF yellowish is commonly used as a cytoplasmic counterstain for nuclear stains, and is applied in Masson's trichrome staining for collagen fibers, Pap staining, and cytological polychromatic staining in histopathology. Light green SF yellowish also induces growth inhibition and local fibrosarcomas in rats and exerts mild pulmonary tumorigenicity in mice. | ||||||||||||||||||||
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Brilliant blue G-250 | 92.05% | Brilliant Blue G-250 is a dye commonly used for the visualization of proteins separated by SDS-PAGE, offering a simple staining procedure and high quantitation. In the Bradford protein assay, protein concentrations are determined by the absorbance at 595 nm due to the binding of Brilliant Blue G-250 to proteins. Brilliant Blue G-250 is a safe highly selective P2×7R antagonist with promising consequent inactivation of NLRP3 inflammasome. | ||||||||||||||||||||
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Brilliant Blue R250 | 95.0% | Brilliant blue R250 (Brilliant Blue R), an anionic dye, is the most popular stain to detect proteins resolved in SDS-PAGE gels. | ||||||||||||||||||||
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Acid blue 9 diammonium | Acid blue 9 diammonium is a triarylmethane dye and inducer. Acid blue 9 diammonium induces chromosomal aberrations in onion root tip meristematic cells. Acid blue 9 diammonium exhibits cytogenetic toxicity to onion root tip meristematic cells. | |||||||||||||||||||||
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Acid Violet 17 | Acid Violet 17 is an acidic dye that can be adsorbed from aqueous solution by orange peel. | |||||||||||||||||||||
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Acid Green 9 | Acid Green 9 is a green dye that can be decolorized by ultrasonic irradiation. | |||||||||||||||||||||
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Fast green FCF free acid | Fast green FCF free acid is a dye that is acid-resistant. Fast Green FCF free acid inhibits α-synuclein aggregation, as well as Aβ, P2X4 receptor and TLR4/Myd88/NF-κB. Fast Green FCF free acid is widely used as a staining agent like quantitative stain for histones at alkaline pH after acid extraction of DNA, and as a protein stain in electrophoresis. Fast Green FCF free acid improves cognitive impairment, depression, relieves pain allergies, and promotes reproductive function. | |||||||||||||||||||||
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Brilliant Blue FCF | 96.70% | Brilliant Blue FCF is an aromatic hydrocarbon, a synthetic dye produced from petroleum and used as a colorant for food and other substances. The solution has a maximum absorption at 628 nm. | ||||||||||||||||||||
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Acid green 3 | Acid green 3 (Pontacyl green B) is an organic compound that can be used as a biological stain. Acid green 3 is a kind of biological materials or organic compounds that are widely used in life science research. | |||||||||||||||||||||
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Acid Blue 7 | Acid Blue 7 is a kind of biochemical reagent. | |||||||||||||||||||||
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References
- [1]. Mittal A, et al. Batch and bulk removal of a triarylmethane dye, Fast Green FCF, from wastewater by adsorption over waste materials. J Hazard Mater. 2009 Apr 30;163(2-3):568-77. [Content Brief]
- [2]. How SC, et al. Examining the inhibitory potency of food additive fast green FCF against amyloid fibrillogenesis under acidic conditions. Food Funct. 2016 Dec 7;7(12):4898-4907. [Content Brief]
- [3]. van Hooft JA. Fast Green FCF (Food Green 3) inhibits synaptic activity in rat hippocampal interneurons. Neurosci Lett. 2002 Feb 1;318(3):163-5. [Content Brief]
- [4]. Wang F, et al. The food additive fast green FCF inhibits α-synuclein aggregation, disassembles mature fibrils and protects against amyloid-induced neurotoxicity. Food Funct. 2021 Jun 21;12(12):5465-5477. [Content Brief]
- [5]. Liu F, et al. Fast green FCF inhibits Aβ fibrillogenesis, disintegrates mature fibrils, reduces the cytotoxicity, and attenuates Aβ-induced cognitive impairment in mice. Int J Biol Macromol. 2021 Feb 15;170:33-41. [Content Brief]
- [6]. Liu J, et al. Fast green FCF prevents postoperative cognitive dysfunction via the downregulation of the P2X4 receptor in mice. Int Immunopharmacol. 2023 Aug;121:110462. [Content Brief]
- [7]. Yang J, et al. Fast Green FCF Attenuates Lipopolysaccharide-Induced Depressive-Like Behavior and Downregulates TLR4/Myd88/NF-κB Signal Pathway in the Mouse Hippocampus. Front Pharmacol. 2019 May 8;10:501. [Content Brief]
- [8]. Xu F, et al. Fast Green FCF Alleviates Pain Hypersensitivity and Down-Regulates the Levels of Spinal P2X4 Expression and Pro-inflammatory Cytokines in a Rodent Inflammatory Pain Model. Front Pharmacol. 2018 May 23;9:534. [Content Brief]
- [9]. Dixit A, et al. ASSESSMENT OF REPRODUCTIVE TOXICITY CAUSED BY FAST GREEN FCF ON MALE SWISS ALBINO MICE. 2012.
