2561471-22-3
2561471-22-3
Chemical Structure
Glutor
- CAS No.: 2561471-22-3
- Formula:C31H32N6O3
- Molecular Weight:536.62
InChIKey: RJNNHMLTCJHHRQ-HKBQPEDESA-N
SMILES: O=C([C@@]1(C)N(C(C2=CC(C3=CC=CC=C3)=NN2C1)=O)CC(C=C4)=CC=C4N5CCOCC5)NCC6=CC=CN=C6
Biological Activity: Glutor is a selective GLUT 1/2/3 inhibitor that can suppress glucose uptake. Glutor can inhibit glycolysis and has anti-tumor activity, inducing cell apoptosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Glutor | 99.54% | Glutor is a selective GLUT 1/2/3 inhibitor that can suppress glucose uptake. Glutor can inhibit glycolysis and has anti-tumor activity, inducing cell apoptosis. | ||||||||||||||||||||
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References
- [1]. Reckzeh ES, et al. Inhibition of Glucose Transporters and Glutaminase Synergistically Impairs Tumor Cell Growth. Cell Chem Biol. 2019;26(9):1214-1228.e25. [Content Brief]
- [2]. Mithlesh Kumar Temre， et al. Glutor, a Glucose Transporter Inhibitor, Exerts Antineoplastic Action on Tumor Cells of Thymic Origin: Implication of Modulated Metabolism, Survival, Oxidative Stress, Mitochondrial Membrane Potential, pH Homeostasis, and Chemosensitivity. Front Oncol. 2022 Jun 30:12:925666. [Content Brief]
