471-53-4
471-53-4
Chemical Structure
18β-Glycyrrhetinic acid
- CAS No.: 471-53-4
- Formula:C30H46O4
- Molecular Weight:470.68
IUPAC Name: (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid
InChIKey: MPDGHEJMBKOTSU-YKLVYJNSSA-N
SMILES: CC1(C)[C@@H](O)CC[C@]([C@@]1([H])CC[C@@]([C@@]2(CC[C@]3(CC[C@](C(O)=O)(C[C@]3(C2=C4)[H])C)C)C)5C)(C)[C@@]5([H])C4=O
Biological Activity: 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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18β-Glycyrrhetinic acid | 99.88% | 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. | ||||||||||||||||||||
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18β-Glycyrrhetinic acid (Standard) | 99.02% | 18β-Glycyrrhetinic acid (Standard) is the analytical standard of 18β-Glycyrrhetinic acid. This product is intended for research and analytical applications. 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhiza uralensis and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. | ||||||||||||||||||||
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18β-Glycyrrhetinic acid-d3 | 98.92% | 18β-Glycyrrhetinic acid-d3 is deuterium labeled 18β-Glycyrrhetinic acid. 18β-Glycyrrhetinic acid is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties. | ||||||||||||||||||||
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DG 381B | DG 381B (compound 62) is a 11β-HSD1 and 11β-HSD2inhibitor. | |||||||||||||||||||||
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Carbenoxolone | 99.9% | Carbenoxolone is a blood-brain barrier-permeable Pannexin1 inhibitor, gap junction (Gap junction) blocker, and β-amyloid 42 inhibitor. Carbenoxolone modulates voltage-gated currents of wild-type and mutant Panx1, and inhibits stimulus-activated Panx1 channel function. Carbenoxolone interacts with stable residues of β-amyloid 42 peptides, fibrils and oligomers, thereby inhibiting their aggregation. Carbenoxolone alleviates liver fibrosis. Carbenoxolone exerts neuroprotective and nootropic effects. Carbenoxolone can be used in studies related to Alzheimer's disease and liver fibrosis. | ||||||||||||||||||||
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18α-Glycyrrhetinic acid | 99.87% | 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis. | ||||||||||||||||||||
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3-epi-18β-Glycyrrhetinic acid | 3-epi-18β-Glycyrrhetinic acid is an inhibitor of 11β-HSD1 and 11β-HSD2, with an IC50 of 0.17 μM against 11β-HSD2. 3-epi-18β-Glycyrrhetinic acid acts as a weak substrate for sulfotransferase 2A1. It serves as a biomarker for the toxicity of licorice-related pseudoaldosteronism. 3-epi-18β-Glycyrrhetinic acid is applicable to studies related to pseudoaldosteronism. | |||||||||||||||||||||
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Obtusilin | Obtusilin is a natural product isolated from Eucalyptus camaldulensis leaves. | |||||||||||||||||||||
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3β-Hydroxy-oleana-11,13(18)-dien-28-oic acid | 3β-Hydroxy-oleana-11,13 (18)-dien-28-oic acid (compound 3) is a triterpenoid compound present in Paeonia japonica and peony calli. 3β-Hydroxy-oleana-11,13 (18)-dien-28-oic acid is also a biotransformation product of oleanolic acid. | |||||||||||||||||||||
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Epikatonic acid | Epikatonic acid (compound 4) is a triterpene. Epikatonic acid can be isolated from Eriope latifolia and Eriope blanchetii. | |||||||||||||||||||||
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β-Amyrenonol | 99.31% | β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids. | ||||||||||||||||||||
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β-Amyrenonol acetate | β-Amyrenonol acetate ((3β)-3-(Acetyloxy)olean-12-en-11-one) is a Triterpenoids product that can be isolated from the barks of Clausena excavata. | |||||||||||||||||||||
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Methyl glycyrrhetinate | Methyl glycyrrhetinate, a 18β-glycyrrhetinic acid analogue, is a dual inhibitor of 11β-HSD1 and 11β-HSD2. | |||||||||||||||||||||
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