534-64-5

Pyrithiamine hydrobromide Chemical Structure
534-64-5

Chemical Structure

Pyrithiamine hydrobromide

  • CAS No.: 534-64-5
  • Formula:C14H20Br2N4O
  • Molecular Weight:420.14

IUPAC Name: 1-((4-amino-2-methylpyrimidin-5-yl)methyl)-3-(2-hydroxyethyl)-2-methylpyridin-1-ium bromide hydrobromide

InChIKey: DMVBWVASDWGFNH-UHFFFAOYSA-M

SMILES: CC1=[N+](C=CC=C1CCO)CC2=C(N=C(N=C2)C)N.[Br-].Br

Biological Activity: Pyrithiamine (hydrobromide) is an inhibitor of thiamine kinase and thiamine pyrophosphate kinase. Pyrithiamine (hydrobromide) competitively inhibits thiamine transport and reduces intracellular levels of thiamine and its phosphates. Pyrithiamine (hydrobromide) is used to study thiamine deficiency with polyneuritic symptoms and Wernicke's encephalopathy[1][2].

Cat. No. Product Name Purity Description Pricing
HY-122273 		Pyrithiamine hydrobromide 96.61% Pyrithiamine (hydrobromide) is an inhibitor of thiamine kinase and thiamine pyrophosphate kinase. Pyrithiamine (hydrobromide) competitively inhibits thiamine transport and reduces intracellular levels of thiamine and its phosphates. Pyrithiamine (hydrobromide) is used to study thiamine deficiency with polyneuritic symptoms and Wernicke's encephalopathy.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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Structural Analogs

References

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