66-71-7
66-71-7
Chemical Structure
o-Phenanthroline
Synonym(s): 1,10-Phenanthroline
- CAS No.: 66-71-7
- Formula:C12H8N2
- Molecular Weight:180.21
IUPAC Name: 1,10-phenanthroline
InChIKey: DGEZNRSVGBDHLK-UHFFFAOYSA-N
SMILES: C12=C(N=CC=C3)C3=CC=C1C=CC=N2
Biological Activity: o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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o-Phenanthroline | 99.95% | o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor. | ||||||||||||||||||||
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o-Phenanthroline-d8 | o-Phenanthroline-d8 is the deuterium labeled o-Phenanthroline. o-Phenanthroline (1,10-Phenanthroline), a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline (1,10-Phenanthroline) forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) is also a MMP inhibitor. | |||||||||||||||||||||
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1,10-Phenanthrolin-2-amine | 1,10-Phenanthrolin-2-amine is an antimycoplasmal agent whose anti-mycoplasmal activity depends on the presence of non-toxic copper. 1,10-Phenanthrolin-2-amine forms a complex with copper, thereby transporting copper into mycoplasma cells, where copper inhibits energy-supplying metabolic processes. 1,10-Phenanthrolin-2-amine can be used in studies of Mycoplasma gallisepticum infection. | |||||||||||||||||||||
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δ-Carboline | δ-Carboline is a nitrogen-containing heterocyclic compound, and its derivatives all exhibit anti-cancer and antibacterial activities. | |||||||||||||||||||||
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8-Hydroxyquinoline | 99.95% | 8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice. | ||||||||||||||||||||
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1,8-Naphthyridine | 1,8-Naphthyridine is a heterocyclic compound with antibacterial and antitumor activities. 1,8-Naphthyridine is promising for research of antibacterial agents and cancers. | |||||||||||||||||||||
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5-Chloro-1,10-phenanthroline | 5-Chloro-1,10-phenanthroline is a metal-organic framework (MOF). | |||||||||||||||||||||
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Benzo[h]quinoline | 99.86% | Benzo[h]quinolone is a widespread environmental pollutant. Benzo[h]quinolone is mutagenic. Benzo(h)quinoline derivatives can serve as G-quadruplex binding agents. | ||||||||||||||||||||
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8-Aminoquinoline | 99.96% | 8-Aminoquinoline is a chelating ligand and intermediate. 8-Aminoquinoline assists metal-catalyzed direct C (sp2)-H and unactivated C (sp3)-H bond functionalization, copper-mediated C-H/C-H coupling, as well as copper/silver-catalyzed aryl C (sp2)-H amination reactions. 8-Aminoquinoline forms cationic Pt (II) complexes with anti-tumor activity. 8-Aminoquinoline is used in research related to latent malaria, glioblastoma, pancreatic adenocarcinoma, adenocarcinoma and biphasic mesothelioma. | ||||||||||||||||||||
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Phenanthridine | Phenanthridine is an aldehyde oxidase 1 (AOX1) substrate, with oxidation by hAOX1 yielding phenanthridone when molecular oxygen, ferricyanide, or dichlorophenolindophenol serves as electron acceptor. | |||||||||||||||||||||
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o-Phenanthroline monohydrate | 99.95% | o-Phenanthroline (1,10-Phenanthroline) monohydrate, a metal chelator, prevents the induction of chromosomal aberrations in streptozotocin-treated cells. o-Phenanthroline monohydrate forms a red chelate with Fe2+ that absorbs maximally at 510 nm. o-Phenanthroline (1,10-Phenanthroline) monohydrate is also a MMP inhibitor. | ||||||||||||||||||||
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References
- [1]. Guan NanMu, et al. Synergistic inhibition between o-phenanthroline and chloride ion on cold rolled steel corrosion in phosphoric acid. Materials Chemistry and Physics Volume 86, Issue 1, 15 July 2004, Pages 59-68.
- [2]. Zi-Qiang Liu, et al. The role of matrix metalloprotease (MMP) to the autolysis of sea cucumber (Stichopus japonicus). J Sci Food Agric. 2019 Oct;99(13):5752-5759. [Content Brief]
