751-03-1
Chemical Structure
Obacunone
- CAS No.: 751-03-1
- Formula:C26H30O7
- Molecular Weight:454.51
IUPAC Name: (1S,3aS,4aR,4bR,6aR,11aR,11bR,13aS)-1-(furan-3-yl)-4b,7,7,11a,13a-pentamethyl-1,6a,7,11a,11b,12,13,13a-octahydrooxepino[4',3':3,4]benzo[1,2-f]oxireno[2,3-d]isochromene-3,5,9(3aH,4bH,6H)-trione
InChIKey: MAYJEFRPIKEYBL-OASIGRBWSA-N
SMILES: O=C(OC1(C)C)C=C[C@]([C@@]1([H])C2)(C)[C@@]3([H])CC[C@]4(C)[C@@]([C@H]5C(O[C@H]4C6=COC=C6)=O)(O5)[C@]3(C)C2=O
Biological Activity: Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Obacunone | 99.75% | Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage. | ||||||||||||||||||||
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Obacunone (Standard) | 99.04% | Obacunone (Standard) is the analytical standard of Obacunone. This product is intended for research and analytical applications. Obacunone is a highly oxidized triterpenoid limonoid isolated from citrus plants. Obacunone exerts its anticancer effects by inducing apoptosis. Obacunone also protects retinal pigment epithelial (RPE) cells from ultraviolet (UV) radiation (UVR)-induced oxidative damage. | ||||||||||||||||||||
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References
- [1]. Chidambara Murthy KN, et al. Obacunone and obacunone glucoside inhibit human colon cancer (SW480) cells by the induction of apoptosis. Food Chem Toxicol. 2011 Jul;49(7):1616-25. [Content Brief]
- [2]. Huang DR, et al. Obacunone protects retinal pigment epithelium cells from ultra-violet radiation-induced oxidative injury. Aging (Albany NY). 2021 Feb 1;13(8):11010-11025. [Content Brief]
- [3]. Xu S, et al. Obacunone activates the Nrf2-dependent antioxidant responses. Protein Cell. 2016 Sep;7(9):684-8. [Content Brief]
