80943-40-4
80943-40-4
Chemical Structure
D,L-erythro-PDMP hydrochloride
- CAS No.: 80943-40-4
- Formula:C23H39ClN2O3
- Molecular Weight:427.02
IUPAC Name: N-((1S,2R)-1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide hydrochloride
InChIKey: HVJHJOYQTSEKPK-QRIJJCFISA-N
SMILES: O[C@@H](C1=CC=CC=C1)[C@H](NC(CCCCCCCCC)=O)CN2CCOCC2.[H]Cl
Biological Activity: D,L-erythro-PDMP hydrochloride is an erythro isomer of PDMP. D,L-erythro-PDMP hydrochloride causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase[1][2].
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D,L-erythro-PDMP hydrochloride | 98.45% | D,L-erythro-PDMP hydrochloride is an erythro isomer of PDMP. D,L-erythro-PDMP hydrochloride causes growth inhibition of cultured rabbit skin fibroblasts. PDMP is an effective inhibitor of UDP-glucose:ceramide glucosyltransferase. | ||||||||||||||||||||
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References
- [1]. Uemura K, et al. Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts. J Biochem. 1990 Oct;108(4):525-30. [Content Brief]
- [2]. Abe A, et al. Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta. 1996 Feb 16;1299(3):333-41. [Content Brief]
Keywords
