92-62-6
92-62-6
Chemical Structure
3,6-Diaminoacridine
- CAS No.: 92-62-6
- Formula:C13H11N3
- Molecular Weight:209.25
IUPAC Name: acridine-3,6-diamine
InChIKey: WDVSHHCDHLJJJR-UHFFFAOYSA-N
SMILES: NC1=CC2=NC3=CC(N)=CC=C3C=C2C=C1
Biological Activity: 3,6-Diaminoacridine is a versatile acridine compound. 3,6-Diaminoacridine exerts antibacterial activity by intercalating into bacterial DNA, interfering with replication and transcription, and inducing bacterial lysis. 3,6-Diaminoacridine is an acridine dye and also a DNA intercalator[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3,6-Diaminoacridine | 98.58% | 3,6-Diaminoacridine is a versatile acridine compound. 3,6-Diaminoacridine exerts antibacterial activity by intercalating into bacterial DNA, interfering with replication and transcription, and inducing bacterial lysis. 3,6-Diaminoacridine is an acridine dye and also a DNA intercalator. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.98
HY-W104195A3,6-Diaminoacridine hydrochloride, 98% -
Similarity Score 0.96
HY-B1741A3,6-Diaminoacridine dihydrochloride -
Similarity Score 0.89
HY-W1973933,6-Diaminoacridine sulfate -
Similarity Score 0.79
HY-B1509ATrypaflavin -
Similarity Score 0.79
HY-B1509BTrypaflavin bromide -
Similarity Score 0.76
HY-U00442CTX1 -
Similarity Score 0.74
HY-D0952Acridine Orange base -
Similarity Score 0.73
HY-101879RAcridine Orange hydrochloride (Standard) -
Similarity Score 0.72
HY-1471823,6-Diamino-9(10H)-acridone -
Explore the MedChemAI to find more analogs
References
- [1]. Kubota Y, et al. Fluorescence decay studies of the DNA-3,6-diaminoacridine complexes. Biophys Chem. 1984;19(1):25-37. [Content Brief]
- [2]. Gamage SA, et al. Synthesis and in vitro evaluation of 9-anilino-3,6-diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum. J Med Chem. 1994;37(10):1486-1494. [Content Brief]
- [3]. Sabolova D, et al. Proflavine/acriflavine derivatives with versatile biological activities. J Appl Toxicol. 2020;40(1):64-71. [Content Brief]
